I was prescribed Hydrocodone/APAP (10/500) in December 2011. Never took more than the prescribed amount (3x Daily). I am now in day 5 since I quit cold turkey. Find information about common, infrequent and rare side effects of Hydrocodone-Acetaminophen Oral. Acetaminophen-hydrocodone oral tablet may make you feel sleepy, dizzy, or lightheaded. Avoid driving a car or using machinery until you know how your body reacts to this medication. Methadone has worked wonders for me as well. I go once a month, get 28 days worth and then have to go back for a new 1 month script. My dosage is very high (130mg/day) but it's been that way for almost 4 years and I've not needed any increase or supplement for breakthrough pain. My GI said to go ahead and take Tylenol if needed. I try not to take any OTC if I can absolutely avoid it, but I bet taking Tylenol only when necessary probably wouldn't hurt anything. Create your own user feedback survey. Hydrocodone is one of the most widely used drugs to fight chronic pain in the United States, serving a consumer base of about 100 million people. that’s all good and dandy but come on… federal government won’t legalize marijuana cause they know that the pharmaceutical companies can’t patton a plant and make money off of it. Find patient medical information for Hydrocodone-Acetaminophen Oral on WebMD including its uses, side effects and safety, interactions, pictures, warnings and user ratings. On October 6, 2014, a Drug Enforcement Administration (DEA) decision to restrict access to hydrocodone combination pain relievers (HCPs) went into effect. Painful joints can be caused by different forms of arthritis. Learn about these conditions so you can take an active role in treatment and management.